Coeliac disease might appear in any period of life, from childhood to seniority. If symptoms show up for the first time in adult age, they might depend on gastrointestinal infections or pregnancy. The starting symptomatology can vary significantly, depending on the lesion extension in the small intestine. Its classic and most common form arises with a general malbsorption, weight loss, diarrea and steatorrea. Minor forms with less symptoms also exist which show selctive malabsorption of nutrients (e.g. iron). Other signs and symptoms can be sideropenic anaemia, ipertransaminasemia, ipostaturalism, ostheoporosis, infertility, alopecia, recurring aphtha stomatitis, enamel ipoplasy. Finally, a silent and asymptomatic form also exists with lesions confined to the duonenum and asbence of any symptoms whatsoever. Several other diseases have been associated with the coeliac disease: herpes dermatitis, Sjögren syndrome, youth mellitus diabetes, autioimmune epathitis, autoimmune tireopathies, Addison syndrome, IgA nephropathy. Among the non-autoimmune diseases there might be epilessy with brain calcifications, Down syndrome and dilatative cardiomiopathy.